Port Pirie Regional Art Gallery is located in the Port Pirie Visitor Information Centre, adjacent to the silos and wharf area in the city of Port Pirie. The Gallery conducts a diverse program of exhibitions annually, with an emphasis on regional South Australian artists. It hosts national touring exhibitions from major Australian cultural institutions and develops exhibitions of topical and community interest. Port Pirie Regional Art Gallery was first established in 1992, exhibiting in the old baggage room of the closed passenger railway station in Port Pirie. The redevelopment of the railway station into the Regional Tourism and Arts Centre in 1994 included a dedicated A class art gallery.

Port Pirie Regional Art Gallery Inc is a not for profit organisation run by a Board of Management generously supported by Port Pirie Regional Council, Country Arts SA, Nyrstar, Southern Cross Television, Pisani Accountants and Business Advisors, Automatic Print and Jan Pana Graphic Design.

Vision
To bring people together to enhance the enjoyment and understanding of the arts.

Values
Port Pirie Regional Art Gallery values the contribution that art makes to society and respects artists' work and rights. The Gallery respects the people who work for the organisation (paid and unpaid) and values the building of positive relationships. The Gallery aims to be transparent in all its dealings, valuing honesty and integrity. It aims to act with professionalism at all times.

Membership
Annual membership is available from $15 for individuals. As well as providing invaluable support to Port Pirie Regional Art Gallery, members receive invitations to exhibition openings and special events, newsletters, and opportunities to visit exhibitions and events regularly. Members also receive information about upcoming workshops, and are offered discounted prices for workshops.